Phenazone, or phenazon, is an analgesic. It was first synthesised by Ludwig Knorr in 1883. It is formed by reducing diortho-dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 C. It crystallizes in needles which melt at 156 C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid.

Synonyms

Analgesine, Antipyrine, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline

See also

Propyphenazone

Chimic Class

• Pyrazole
• Pyrazolinone

Pharmacology

• Analgesics
• Antipyretic
• NSAID

Adverse effects

• Allergy to pyrazolones
• Nausea
• Agranulocytosis

hepatotoxic